Harry Sahle contributes a feature called Hickory (originally Acorn Acres) to All Humor. There's some really great cartooning from Sahle here. The rough and tumble rural-based humor of Hickory proved popular enough that it eventually led to him getting his own comic book.
Even the lesser features in the comic are a lot of fun. Take a gander at the simple, appealing cartooning of Al Stahl on Bozo the Hobo.
And then there's the flat out weirdness that is Atomictot! Some Atomictot stories are drawn by Gill Fox -- others (in a truly odd drawing style) are clearly by another hand (Ernie Hart?).
If you like what you see here, check out the links I posted earlier to see more. In the meantime, I'm just going to wish we had comics of this sort (as well as the horror anthologies I've been posting from) on the market now. I would so much rather read well-drawn wacky, goofball humor stories and over the top horror/suspense tales the likes of which I've been posting here, than the turgid, overly serious super hero books dominating the market today.